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The Melting People of The Brazilian village of Araras – Xeroderma Pigmentosum (aka “XP”)

The affected community has the highest rate of XP, a condition that prevents the skin from being able to repair damage done by UV rays.

Doctor Vikram Singh Yadav has one of the better videos explaining Xeroderma Pigmentosum (XP) and provides a simple explanation:

Normally when you walk in sunlight, ultraviolet part of sunlight damages the cells of epidermis and DNA, this damage is usually repaired by set of enzymes known as nucleotide excision repair enzymes. But in this condition this ability to repair is lost. So exposure to sunlight must be avoided in such conditions. When exposed many times leads to formation of squamous cell carcinoma and malignant melanoma which is the cause of death in such patients who usually dies in their teenage group. Earlier symptoms are freckles on face, sunburn on minimal exposure to sunlight, skin blisters etc. Watch our previous video to have pics and video of Xeroderma Pigmentosum.


araras brazil XP xeroderma pigmentosum hospital

real life XP prosthetic face as seen in boardwalk empire

xeroderma pigmentosum XP

unable to repair the skin from sun damage